ICONS: Samuel Morse's Telegraph, Frederick Douglass, Sewing Machine
Captain Charles Wilkes circumnavigates Antarctica, claiming it for the United States on January 19, 1840.
William Henry Harrison wins the 1840 presidential election, defeating incumbent Martin Van Buren.
The August 9, 1842, Webster-Ashburton Treaty formally designates the border separating the United States and Canada.
On May 24, 1844, Samuel B. Morse sends the message, "What hath God wrought" over the first telegraph line from Washington, DC, to Baltimore, MD.
Ireland's "Potato Famine" results in an influx of Irish immigrants to the United States beginning in 1845.
Alexander Cartwright and his New York Knickerbockers codify the "Rules of Baseball" in 1845.
Frederick Douglass publishes Narrative of the Life of Frederick Douglass, an American Slave in 1845.
Elias Howe patents the sewing machine on September 10, 1846.
During the February 22-23, 1847, Battle of Buena Vista, General Taylor's U.S. Army of 4800 men defeats Mexico's 15,000-man force lead by General Santa Anna.
The American Medical Association is founded in Philadelphia on May 7, 1847.
On January 24, 1848, James Marshall discovers gold near Sutter's Fort, California. The discovery of gold is the beginning of the California Gold Rush of 1849.
The 1849 Treaty of Guadalupe Hidalgo ends the Mexican-American War. In exchange for $15 million and settling $3.25 million in American claims, Mexico cedes approximately 500,000 square miles of territory in the western and southwestern United States.
Elizabeth Blackwell receives the first medical degree awarded to a woman on January 23, 1849, from the Medical Institute of Geneva, NY.
Henry David Thoreau publishes "Resistance to Civil Government," later known as "Civil Disobedience," in 1849.
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